[PDF] Improving Effect of Extract of Ganoderma lucidum in Atherosclerosis from LDL Receptor Knockout Mouse | Semantic Scholar (2025)

It is suggested that boiled tuna extract attenuates the progression of obesity by stimulating fatty acid oxidation through the upregulation of AMPK genes, as well as by inhibiting the synthesis of adipogenic and lipogenic enzymes.

The results of the present study indicated that grape stalk extract may be a potent functional food ingredient for preventing obesity, hepatic steatosis and type 2 diabetes.

The results show that GPs has good effects on the treatment of hyperlipidemia induced by high lipid diet in rats, and the possible anti-hyperlipidemic mechanism maybe those GPs can regulate the disorder of lipid metabolism as well as ameliorate hepatic function.

The results suggested that Angelica keiskei and turmeric extract complex might have synergistic effect in lowering total cholesterol, LDL-cholesterol and triglyceride in hyperlipidemic rats.

Findings indicate that subcutaneous injection of an 11beta-HSD1 inhibitor allows for the targeting of the enzyme in not only liver, but also adipose tissue, and attenuates many metabolic syndrome risk factors, with more pronounced effects in cases of severe obesity and hyperlipidemia.

The effect of a powder prepared from Ganoderma lucidum mushroom on the blood pressure and lipid levels of spontaneously hypertensive rats (SHR) were examined.

The results suggest that Dodam-tang suppresses the brain edema formation through the suppression of the iNOS, MMP-9 and GFAP, but the neuroprotective effect against the cerebral infarct are not distinct.

It is suggested that, although obesity and hyperlipidemia exert individual pathological effects, the combination of the two has the potential to exert an additive effect on NAFLD and IR but not atherosclerosis in this mouse model.

Fractionated extracts of Smilacis glabrae rhizoma have potential as an agent of atherosclerosis and other chronic inflammatory diseases including diabetes, hypertension, and arthritis, according to this study.

It is suggested that upregulation of the receptor could have therapeutic potential for the treatment of atherosclerosis and may in part be due to increased LDL cholesterol levels.

It is reported that the PPARγ-specific agonists rosiglitazone and GW7845 strongly inhibited the development of atherosclerosis in LDL receptor‐deficient male mice, despite increased expression of the CD36 scavenger receptor in the arterial wall.

Preliminary study indicated that antiangiogenic effect may be involved antitumor activity of G lucidum.

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